April 2014

Author: Marilin Rosa, MD, Department of Anatomic Pathology and Women’s Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, Florida, USA

Reviewer: Christopher van den Bussche, Dept. of Pathology, Johns Hopkins Hospital, Baltimore, MD, U.S.A.

A 40 year-old female smoker presented to her primary care physician complaining of a painful lesion on her right breast. The patient reported having a scant non-bloody nipple discharge. She also noted that the lesion had slowly increased in size during the past 5 months. The patient had no personal or family history of breast cancer and had never had a mammogram. Upon physical examination, a smooth, ?rm mass approximately 2.0 cm in diameter could be located centrally beneath the nipple. Her skin was tender but without ulceration or erythema. A fine needle aspiration biopsy (FNA) was performed without complications.

Fig 1 2014 April
Fig. 1 10x
Fig 2 2014 April
Fig. 2 10x
Fig 3 2014 April
Fig. 3 40x
Fig 4 2014 April
Fig. 4 40x

What is the most likey diagnosis?