November 2011

Pap Test in an 82-Year-Old Woman with Vaginal Bleeding and an Endocervical Polyp 

Xiangbai Chen, MD1, Walid E. Khalbuss, MD PhD2, Curtis Goldblatt, MD1, and Liron Pantanowitz, MD2

1. Department of Pathology, Conemaugh Memorial Hospital, Johnstown, PA, USA.
2. Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.


Fig. 1  Pap test showing many tumor cells dispersed among mature squamous cells (SurePath, Pap stain, original magnification x200).
Fig. 2 Pap test showing tumor cells of varying size with round nuclei and prominent nucleoli (SurePath, Pap stain, original magnification x400).
Fig. 3 Histopathology of the cervical polyp showing sheets of poorly differentiated tumor cells with prominent nucleoli and focal melanin pigment (H&E stain, original magnification x400).
Fig. 4 Strong Melan-A immunoreactivity is shown in melanoma tumor cells surrounding blood vessels (immunohistochemical stain, original magnification x400).

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