Liquid Biopsy and Cytopathology: The Perfect Marriage
Prof. Umberto Malapelle, MD
Department of Public Health, University Federico II of Naples, Italy
University Frederico II of Naples, Italy
In the landscape of Predictive Molecular Pathology, the assessment of the genomic landscape for patients affected by solid tumours is crucial. In this scenario, liquid biopsy, including all the body fluids, represents not only an alternative but a complementary source of tumour nucleic acids to tissue in order to guarantee the best clinical management for these patients. The Cytopathology Laboratories in which happens all the managment of cytopatological samples, including all the supernaatants, represent the home for all the people aiming to work in the landscape of liquid biopsy.
Date: Thursday, 20. November 2025
Time: 1:00 PM (13:00) European Central Time
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Prof. Umberto Malapelle
Department of Public Health, University Federico II of Naples, Italy
Associate Professor in School of Medicine, University of Naples Federico II.
Currently is the Chair of Predictive Molecular Pathology Laboratory, Department of Public Health of University Federico II of Naples and serves as Scientific Secretary of the International Society of Liquid Biopsy and Editor in Chief of The Journal of Liquid Biopsy.
His main research interest is in the field of genomic biomarkers validation and testing for predictive information in the field of lung cancer, metastatic colorectal cancer, melanoma and gastrointestinal stromal tumor.
Moreover, he has developed skills in tailoring Next Generation Assays for several different applications with a special focus on the simultaneously detection of clinically relevant alterations (i.e., EGFR mutations, ALK traslocation, PD–L1 expression) in the routine setting including handling of different sample types, such as tissues and/or liquid biopsy specimens.